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Diabetes Care

GLI M 80 500

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Gliclazide + Metformin is used to treat type 2 diabetes mellitus. It is prescribed along with diet and exercise to improve blood glucose control in adults.

  • Gliclazide: A sulfonylurea that stimulates the pancreas to release more insulin, helping to lower blood glucose levels.
  • Metformin: A biguanide that decreases glucose production in the liver, delays glucose absorption in the intestines, and improves insulin sensitivity.

Hypoglycemia (low blood glucose level), Headache, Upper respiratory tract infection, Dizziness, Nausea, Diarrhea, Flatulence

  • Take this medicine with food to reduce stomach upset.
  • Monitor blood sugar levels regularly to avoid hypoglycemia, especially if combined with other antidiabetic medications or alcohol.
  • Inform your doctor if you are scheduled for surgery, as certain precautions may be necessary.
  • Notify your doctor immediately if you experience rapid breathing, nausea, vomiting, or abdominal pain, as these may be signs of lactic acidosis.
  • Regular liver function tests may be recommended. Report any symptoms like abdominal pain, loss of appetite, or jaundice (yellowing of the eyes or skin).
01

What is Gliclazide + Metformin?

It is a combination of two antidiabetic medicines used to treat type 2 diabetes. Gliclazide increases insulin secretion, while Metformin reduces glucose production and improves insulin sensitivity.

02

What are the possible side effects?

Common side effects include hypoglycemia, nausea, stomach pain, diarrhea, headache, and upper respiratory tract infection. Rarely, lactic acidosis and vitamin B12 deficiency may occur with prolonged use.

03

Can Gliclazide + Metformin cause hypoglycemia?

Yes, especially if meals are missed, alcohol is consumed, or other antidiabetic medications are used. Keep glucose tablets, honey, or juice on hand for quick relief if symptoms like dizziness, sweating, or fast heartbeat occur.

04

Can it cause lactic acidosis?

Yes, although rare, Metformin can lead to lactic acidosis, especially in individuals with kidney disease, elderly patients, or those consuming large amounts of alcohol. Symptoms include muscle pain, tiredness, breathing difficulties, and nausea. Seek medical attention immediately if these occur.

05

Can Gliclazide + Metformin lead to vitamin B12 deficiency?

Yes, long-term use may interfere with vitamin B12 absorption, potentially causing deficiency. Symptoms may include tingling or numbness, weakness, and balance issues. An annual B12 supplement may be recommended.

06

Are there any conditions in which Gliclazide + Metformin should not be used?

Avoid use if you have a known allergy to any of the ingredients, moderate to severe kidney disease, or metabolic acidosis, including diabetic ketoacidosis.

07

Is it safe to consume alcohol with this medication?

No, alcohol increases the risk of hypoglycemia and lactic acidosis. It is best to avoid alcohol while taking this combination.

Disclaimer

Disclaimer

: The information provided on this page is for informational and educational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified healthcare provider with any questions you may have regarding a medical condition.
WRITTEN BY
Dr. Helan, PharmD
REVIEWED BY
Dr. Lakshmi MBBS, MD
LAST UPDATED
Nov 2, 2026
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"Medingen Generic medicine is valuable reasonable price,but some medicines are not available need to improve stock all medicines,fast courier service is good,immediate responsible.thanks."

Priya Anup
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"Excellent service! Got my medicines the very next day. Utmost care was taken to pack the medicines, with the package being very neatly and tightly packed. The delivery was very quick. Customer service was very good, with regular updates over whatsapp. I highly recommend Medingen for your medicine purchases."

Save 52%
GLI M 80 500 - View 1
Diabetes Care

GLI M 80 500

₹63₹132Save ₹69.00
Inclusive of all taxes
In Stock
Check Delivery Date
Enter your pincode
WHO/GMP Certified
Fast Delivery
Safe & Secure Payment
7 Days Return
Pharmacist Support
Have questions?
Call Now

Gliclazide + Metformin is used to treat type 2 diabetes mellitus. It is prescribed along with diet and exercise to improve blood glucose control in adults.

  • Gliclazide: A sulfonylurea that stimulates the pancreas to release more insulin, helping to lower blood glucose levels.
  • Metformin: A biguanide that decreases glucose production in the liver, delays glucose absorption in the intestines, and improves insulin sensitivity.

Hypoglycemia (low blood glucose level), Headache, Upper respiratory tract infection, Dizziness, Nausea, Diarrhea, Flatulence

  • Take this medicine with food to reduce stomach upset.
  • Monitor blood sugar levels regularly to avoid hypoglycemia, especially if combined with other antidiabetic medications or alcohol.
  • Inform your doctor if you are scheduled for surgery, as certain precautions may be necessary.
  • Notify your doctor immediately if you experience rapid breathing, nausea, vomiting, or abdominal pain, as these may be signs of lactic acidosis.
  • Regular liver function tests may be recommended. Report any symptoms like abdominal pain, loss of appetite, or jaundice (yellowing of the eyes or skin).
01

What is Gliclazide + Metformin?

It is a combination of two antidiabetic medicines used to treat type 2 diabetes. Gliclazide increases insulin secretion, while Metformin reduces glucose production and improves insulin sensitivity.

02

What are the possible side effects?

Common side effects include hypoglycemia, nausea, stomach pain, diarrhea, headache, and upper respiratory tract infection. Rarely, lactic acidosis and vitamin B12 deficiency may occur with prolonged use.

03

Can Gliclazide + Metformin cause hypoglycemia?

Yes, especially if meals are missed, alcohol is consumed, or other antidiabetic medications are used. Keep glucose tablets, honey, or juice on hand for quick relief if symptoms like dizziness, sweating, or fast heartbeat occur.

04

Can it cause lactic acidosis?

Yes, although rare, Metformin can lead to lactic acidosis, especially in individuals with kidney disease, elderly patients, or those consuming large amounts of alcohol. Symptoms include muscle pain, tiredness, breathing difficulties, and nausea. Seek medical attention immediately if these occur.

05

Can Gliclazide + Metformin lead to vitamin B12 deficiency?

Yes, long-term use may interfere with vitamin B12 absorption, potentially causing deficiency. Symptoms may include tingling or numbness, weakness, and balance issues. An annual B12 supplement may be recommended.

06

Are there any conditions in which Gliclazide + Metformin should not be used?

Avoid use if you have a known allergy to any of the ingredients, moderate to severe kidney disease, or metabolic acidosis, including diabetic ketoacidosis.

07

Is it safe to consume alcohol with this medication?

No, alcohol increases the risk of hypoglycemia and lactic acidosis. It is best to avoid alcohol while taking this combination.

Disclaimer

Disclaimer

: The information provided on this page is for informational and educational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified healthcare provider with any questions you may have regarding a medical condition.
Manufacturer Details
Country of Origin: India
Editorial Info
WRITTEN BY
Dr. Helan PharmD
Clinical Nutritionist
REVIEWED BY
Dr. Lakshmi MBBS, MD
Pharmaceutical Sciences Expert
Last Updated: Nov 2, 2026
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User Reviews

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on Google
4.9
★★★★☆
89 Ratings
5
4
3
2
1
KG Rajan
★★★★☆

"Medingen Generic medicine is valuable reasonable price,but some medicines are not available need to improve stock all medicines,fast courier service is good,immediate responsible.thanks."

Priya Anup
★★★★★

"Excellent service! Got my medicines the very next day. Utmost care was taken to pack the medicines, with the package being very neatly and tightly packed. The delivery was very quick. Customer service was very good, with regular updates over whatsapp. I highly recommend Medingen for your medicine purchases."

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