01
What is Gliclazide + Metformin?
It is a combination of two antidiabetic medicines used to treat type 2 diabetes. Gliclazide increases insulin secretion, while Metformin reduces glucose production and improves insulin sensitivity.
02
What are the possible side effects?
Common side effects include hypoglycemia, nausea, stomach pain, diarrhea, headache, and upper respiratory tract infection. Rarely, lactic acidosis and vitamin B12 deficiency may occur with prolonged use.
03
Can Gliclazide + Metformin cause hypoglycemia?
Yes, especially if meals are missed, alcohol is consumed, or other antidiabetic medications are used. Keep glucose tablets, honey, or juice on hand for quick relief if symptoms like dizziness, sweating, or fast heartbeat occur.
04
Can it cause lactic acidosis?
Yes, although rare, Metformin can lead to lactic acidosis, especially in individuals with kidney disease, elderly patients, or those consuming large amounts of alcohol. Symptoms include muscle pain, tiredness, breathing difficulties, and nausea. Seek medical attention immediately if these occur.
05
Can Gliclazide + Metformin lead to vitamin B12 deficiency?
Yes, long-term use may interfere with vitamin B12 absorption, potentially causing deficiency. Symptoms may include tingling or numbness, weakness, and balance issues. An annual B12 supplement may be recommended.
06
Are there any conditions in which Gliclazide + Metformin should not be used?
Avoid use if you have a known allergy to any of the ingredients, moderate to severe kidney disease, or metabolic acidosis, including diabetic ketoacidosis.
07
Is it safe to consume alcohol with this medication?
No, alcohol increases the risk of hypoglycemia and lactic acidosis. It is best to avoid alcohol while taking this combination.
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