PREGAHEM NT TABLET
Product Description
PREGAHEM NT TABLET tablet containing PREGABALIN + NORTRIPTYLINE is a prescription combination medicine used to treat neuropathic pain caused by diabetic nerve damage, post-herpetic neuralgia, sciatica, cervical radiculopathy, and peripheral neuropathy. Pregabalin calms overactive pain-signaling nerves, while nortriptyline, a tricyclic antidepressant, increases serotonin and norepinephrine levels to strengthen the brain’s natural pain-control pathways. This dual mechanism helps reduce burning, tingling, electric-shock sensations, numbness, and pain-related sleep disturbance. PREGAHEM NT TABLET tablet is commonly prescribed when single-drug therapy does not provide adequate relief. PREGAHEM NT TABLET tablet dosage is started low and adjusted gradually based on pain severity, kidney function, and tolerability. Common PREGAHEM NT TABLET side effects include dizziness, sleepiness, dry mouth, constipation, and blurred vision. Regular use may improve sleep, mobility, and quality of life in chronic nerve pain patients.
Pharmacist Note
Take PREGAHEM NT TABLET tablet preferably at night because drowsiness and dizziness are common during the first week. Do not stop it suddenly, as both pain rebound and withdrawal symptoms such as sweating, anxiety, insomnia, or nausea may occur. Rise slowly from sitting or lying positions to reduce dizziness and fall risk.
Uses & Benefits
used in the treatment of neuropathic pain.
Diabetic Neuropathy Relief: [{product_name}] tablet is widely used to reduce burning feet, numbness, tingling, and night pain caused by diabetic nerve damage. The combination supports better day-and-night symptom control and improved sleep comfort.
Sciatica and Radicular Pain: [{product_name}] tablet may help in chronic back or neck pain that radiates into the arms or legs due to nerve compression. It helps reduce shooting pain, hypersensitivity, and sleep-disrupting discomfort caused by irritated nerves.
Post-Herpetic Neuralgia: [{product_name}] tablet can be prescribed for persistent nerve pain after shingles infection. It helps calm damaged nerves and reduces sharp, stabbing, or electric-shock-like sensations over time.
Peripheral Neuropathy Support: [{product_name}] tablet may improve comfort in chronic peripheral nerve disorders linked to metabolic disease, nerve injury, or compression. Regular use can support better mobility and daily functioning.
Side Effects
common:
moderate:
rare:
How to Use & Safety Advice
[{"icon":"dosage","title":"Dosage","description":"[{product_name}] tablet dosage is decided by your doctor based on the type of nerve pain, kidney function, age, and sleep disturbance severity. Low starting doses are usually preferred to reduce dizziness and daytime sedation."},{"icon":"timing","title":"Timing","description":"Take [{product_name}] tablet with or without food at the same time every day. Bedtime dosing is often preferred because it may cause drowsiness and can improve night pain control."},{"icon":"limit","title":"Limit","description":"Do not exceed the prescribed [{product_name}] dosage, as higher doses may increase severe drowsiness, blurred vision, poor coordination, and fall risk. Never stop suddenly without doctor guidance."},{"icon":"consistency","title":"Consistency","description":"Regular use of [{product_name}] tablet is important for stable neuropathic pain relief. Missing doses may worsen nerve pain, disturb sleep, or trigger withdrawal symptoms."}]
[{"icon": "pregnancy", "title": "Pregnancy", "description": "[{product_name}] tablet should only be used during pregnancy if clearly prescribed after careful medical risk-benefit assessment."}, {"icon": "alcohol", "title": "Alcohol", "description": "Avoid alcohol because it can significantly worsen dizziness, sleepiness, dry mouth, and poor coordination caused by [{product_name}] tablet."}, {"icon": "driving", "title": "Driving", "description": "[{product_name}] tablet may impair alertness, reaction time, and coordination. Avoid driving until you know how it affects you."}, {"icon": "kidney", "title": "Kidney", "description": "Dose adjustment may be needed in kidney disease because the pregabalin component is cleared through the kidneys. Use under regular medical supervision."}, {"icon": "elderly", "title": "Elderly", "description": "Older adults may be more sensitive to dizziness, constipation, urinary retention, and falls. Lower starting doses are generally safer."}, {"icon": "children", "title": "Children", "description": "[{product_name}] tablet is generally not recommended in children unless specifically prescribed by a neurologist or pain specialist."}]
Details
Benefits
Pregabalin + Nortriptyline is prescribed for:Neuropathic pain (pain caused by damaged or overactive nerves).
How It Works
- Pregabalin: Modulates calcium channel activity in nerve cells, calming overactive nerves and reducing pain sensations.
- Nortriptyline: A tricyclic antidepressant that increases serotonin and noradrenaline levels in the brain, which block pain signals and improve mood.
Together, they effectively alleviate neuropathic pain.
Side Effects
Constipation, Difficulty urinating, Weight gain, Sleepiness, Dizziness, Tiredness, Blurred vision, Dry mouth, Increased heart rate, Orthostatic hypotension (low blood pressure upon standing), Uncoordinated body movements
Expert's Advice
- Consistent Use:Take as prescribed without skipping doses to ensure maximum effectiveness.
- Avoid Sudden Discontinuation:Taper off gradually under medical supervision to prevent withdrawal symptoms like nausea, anxiety, or sweating.
- Alcohol Avoidance:Avoid alcohol, as it can increase side effects like drowsiness and dizziness.
- Weight Management:Follow a healthy diet and engage in regular physical activity to minimize weight gain.
- Driving and Alertness:Avoid driving or operating heavy machinery until you know how the medication affects you, as it may cause drowsiness or sudden sleep episodes.
- Monitor Mood Changes:Report any unusual mood changes, depression, or suicidal thoughts to your doctor immediately.
- Avoid Grapefruit:Grapefruit and its juice can interact with the medication, potentially increasing side effects.
Frequently Asked Questions
Q. What is Pregabalin + Nortriptyline used for?
This combination is used to treat neuropathic pain by calming damaged nerves and blocking pain signals in the brain.
Q. Can I stop taking it if my pain is relieved?
No, stopping suddenly may cause withdrawal symptoms. Consult your doctor before discontinuing the medication.
Q. How to manage weight gain?
Maintain a balanced, low-calorie diet, avoid high-fat and junk foods, and exercise regularly. A dietitianâs guidance can be helpful.
Q. What should I do if I miss a dose?
Take the missed dose as soon as you remember. If it's close to the next dose, skip the missed one and resume your normal schedule. Do not double the dose.
Q. Does this medication affect sexual health?
Yes, it may cause decreased libido, erectile dysfunction, or difficulty reaching orgasm. Discuss these side effects with your doctor if they occur.
Q. How long does it take for Pregabalin + Nortriptyline to work?
You may experience initial relief within 2 weeks, but full effects often take 2-3 months.
Q. Are there serious side effects I should watch for?
Rare but serious side effects include mood changes, palpitations, difficulty walking, or signs of infection (e.g., fever, sore throat). Contact your doctor if these symptoms appear.
Q. Can I drive while taking this medication?
No, the medication may impair focus or cause sudden sleep episodes. Avoid driving or operating machinery until you are sure it does not affect you.
Q. How should I store this medication?
Store in a cool, dry place away from direct sunlight and out of reach of children. Dispose of unused medication responsibly to prevent misuse.