Composition:

ACECLOFENAC 100MG PARACETAMOL 325MG SERRATIOPEPTIDASE 15MG

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SIGNOFLAM

Name: SIGNOFLAM
Brand: LUPIN LTD.
SKU: 41493
Price: 136.00 INR
Availability: InStock
Rating: 4.9 (88 reviews)

LUPIN LTD.

Composition

ACECLOFENAC 100MG PARACETAMOL 325MG SERRATIOPEPTIDASE 15MG

₹136

10'S

OUR RECOMMENDED ALTERNATIVE

SAVE 70%

joint and muscle care

ACTIFLOX SP

Composition:ACECLOFENAC 100MG PARACETAMOL 325MG SERRATIOPEPTIDASE 15MG10'S

Brand: PURE & CURE HEALTHCARE PVT. LTD.

In Stock

₹37.00₹125.00Saving: ₹88.00

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Substitutes of SIGNOFLAM

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70% OFF

ACECLOWAL SP FORTE

Aceclofenac 100mg + Paracetamol 325mg + Serratiopeptidase 15mg

₹33.00

67% OFF

ACTIFLOX SP

Aceclofenac 100mg + Paracetamol 325mg + Serratiopeptidase 15mg

₹37.00

SIGNOFLAM tablet is a combination medicine containing Aceclofenac, Serratiopeptidase, and Paracetamol, belonging to the class of anti-inflammatory and analgesic drugs. It is commonly prescribed to relieve pain, inflammation, and swelling associated with conditions like arthritis, muscle injuries, and post-operative pain. The formulation helps reduce fever, ease stiffness, and improve mobility by targeting multiple pathways involved in pain and inflammation. SIGNOFLAM tablet is available in different strengths to suit individual patient needs and should be used under medical supervision for effective symptom management and quicker recovery.

Pharmacist Note

Always take SIGNOFLAM tablet after food to reduce the risk of stomach irritation. Avoid combining it with other painkillers unless prescribed, as this may increase the risk of side effects. Stay hydrated and inform your doctor if you have any history of stomach ulcers, liver issues, or allergies.

Pain Relief in Musculoskeletal Conditions

SIGNOFLAM tablet helps relieve pain associated with muscle strains, sprains, and joint disorders. It reduces inflammation and improves mobility, making daily activities more comfortable for patients suffering from acute or chronic pain conditions.

Management of Arthritis

SIGNOFLAM tablet is widely used in conditions like osteoarthritis and rheumatoid arthritis. It helps decrease joint swelling, stiffness, and pain, allowing better joint function and improved quality of life when used regularly as prescribed.

Post-surgical and Injury Recovery

SIGNOFLAM tablet supports recovery after surgeries or injuries by reducing swelling and discomfort. It helps accelerate healing and allows patients to resume normal activities faster with better pain control.

Fever and General Pain Relief

SIGNOFLAM tablet also helps in reducing fever and mild to moderate body pain. It is useful in conditions like infections or flu where pain and fever occur together, providing overall symptomatic relief.

While generally safe and well-tolerated, high doses or sensitivity can cause some side effects.

Type

Symptoms

Severity

Common

Nausea, vomiting, indigestion, stomach pain

Common

Dizziness, headache, diarrhea

Occasional

Serious

Liver issues, allergic reactions, severe stomach ulcers

Rare

Dosage

The dose of SIGNOFLAM tablet depends on the severity of the condition and the patient’s medical history. Always follow your doctor’s prescribed dosage and never adjust it on your own.

Timing

Take SIGNOFLAM tablet with food or after meals to minimize stomach discomfort. Swallow it whole with water and avoid crushing or chewing unless advised.

Limit

Do not exceed the recommended dose of SIGNOFLAM tablet, as overdose may lead to serious liver damage or other complications. Seek medical help immediately if overdose is suspected.

Consistency

Take SIGNOFLAM tablet at the same time each day for better effectiveness. Consistent use helps maintain stable drug levels in the body and ensures optimal pain relief.

SIGNOFLAM tablet works through a combination of actions to relieve pain and inflammation. It blocks the production of certain chemical messengers responsible for pain and swelling, while also reducing fever. Additionally, it helps break down inflammatory proteins at the affected site, improving blood flow and speeding up healing, which results in reduced discomfort and better mobility.

Pregnancy

SIGNOFLAM tablet should be used during pregnancy only if clearly needed and prescribed by a doctor. Self-medication may pose risks to the developing baby, especially in later stages.

Alcohol

Avoid consuming alcohol while taking SIGNOFLAM tablet, as it may increase the risk of liver damage and stomach irritation. Combining both can worsen side effects significantly.

Driving

SIGNOFLAM tablet may cause dizziness or drowsiness in some individuals. If you experience such symptoms, avoid driving or operating heavy machinery until you feel normal.

Kidney

Patients with kidney problems should use SIGNOFLAM tablet cautiously. Dose adjustments may be required, and regular monitoring is advised to prevent complications.

Elderly

Older adults may be more sensitive to the effects of SIGNOFLAM tablet. Lower doses and careful monitoring are recommended to reduce the risk of side effects.

Children

SIGNOFLAM tablet should not be given to children unless prescribed by a doctor. The safety and dosage must be carefully evaluated by a healthcare professional.

Warfarin (Blood thinner)

May increase the risk of bleeding when taken with SIGNOFLAM tablet. Careful monitoring is advised.

High

Metoclopramide (Antiemetic)

May increase the absorption of SIGNOFLAM tablet, making it act faster.

Moderate

Colestyramine (Lipid-lowering agent)

May reduce the absorption and effectiveness of SIGNOFLAM tablet.

Moderate

Ibuprofen (Pain reliever)

May increase the risk of stomach irritation and ulcers when combined with SIGNOFLAM tablet.

High

What are the uses of SIGNOFLAM tablet?

SIGNOFLAM tablet uses include relief from pain, inflammation, and swelling in conditions like arthritis, muscle injuries, and post-surgical recovery. It also helps reduce fever and improves mobility, making it a commonly prescribed medicine for combined pain and inflammation management.

Can I take SIGNOFLAM tablet daily?

SIGNOFLAM tablet can be taken daily if prescribed by your doctor. Long-term use should be monitored to avoid side effects, especially related to the stomach, liver, or kidneys. Always follow the recommended duration and dosage for safe use.

What are the common side effects of SIGNOFLAM tablet?

SIGNOFLAM tablet side effects may include nausea, stomach pain, dizziness, or indigestion. These are usually mild and temporary, but if symptoms persist or worsen, it is important to consult a doctor for further evaluation.

Can SIGNOFLAM tablet be taken on an empty stomach?

It is recommended to take SIGNOFLAM tablet after food to reduce the risk of stomach irritation. Taking it on an empty stomach may increase discomfort and the chances of gastric side effects.

Is SIGNOFLAM tablet safe for long-term use?

SIGNOFLAM tablet uses for long-term treatment should only be under medical supervision. Prolonged use may increase the risk of side effects, especially liver or stomach-related issues, so regular check-ups are important.

Are SIGNOFLAM and ACTIFLOX SP the same?

Yes, SIGNOFLAM and ACTIFLOX SP contain the same active salt (ACECLOFENAC 100MG + PARACETAMOL 325MG + SERRATIOPEPTIDASE 15MG) in the same strength and provide identical therapeutic efficacy, meeting strict quality and safety standards.

• WHO – https://www.who.int/news-room/fact-sheets/detail/pain-management
• NICE – https://www.nice.org.uk/guidance/ng59
• Mayo Clinic – https://www.mayoclinic.org/drugs-supplements
• NHS – https://www.nhs.uk/conditions/pain/
• ICMR – https://main.icmr.nic.in/content/disease-guidelines

Disclaimer

: The information provided on this page is for informational and educational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified healthcare provider with any questions you may have regarding a medical condition.

WRITTEN BY

Dr. Helan, PharmD

REVIEWED BY

Dr. Lakshmi MBBS, MD

LAST UPDATED

Nov 2, 2026

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Marketer Details

LUPIN LTD.

Country of Origin

India

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User Reviews

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"Excellent service! Got my medicines the very next day. Utmost care was taken to pack the medicines, with the package being very neatly and tightly packed. The delivery was very quick. Customer service was very good, with regular updates over whatsapp. I highly recommend Medingen for your medicine purchases."